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How big is the en suite? Could you partition a bit off for a washer/dryer and still have room for the shower/toilet. If it's going to be a guest bedroom I think it would definitley be a negative to get rid of it, plus when it's redecorated, if it's only being used occasionally when guest are there mold shouldn't be an issue.
If you don't like it / use it and will use it when turned into something else then it's not a bad idea.
It will definitely affect the resale value / appeal though.