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It's even further from Toddington to Reading but half an hour is more typical. In theory they are every 15 milesish and never more than 28 miles apart, but there are gaps. A trucker probably knows them better than I and so can plan a loo break if they aren't getting pressurised to get to their destination, which they probably are.
Is there a thread for favourite motorway services? I'm quite partial to Leicester Forest East and Beaconsfield for very different reasons.
Do you even M25? (though slightly better now we have the Cobham services added)