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It's even further from Toddington to Reading but half an hour is more typical. In theory they are every 15 milesish and never more than 28 miles apart, but there are gaps. A trucker probably knows them better than I and so can plan a loo break if they aren't getting pressurised to get to their destination, which they probably are.
Is there a thread for favourite motorway services? I'm quite partial to Leicester Forest East and Beaconsfield for very different reasons.
Services every half hour or so? Plan for a piss.
I'd have thought some of the problem is lots of traffic and a fairly rigid delivery slot without a lot of contingency time discourages breaks.