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Couldn't you extend a wall underneath the stairs, make the entry to the toilet from there from the hallway and snug the washing machine underneath the stairs?
Having double doors between the stink in the toilet and the living room is common practice on the continent where I am from.
Also, if you get the enfilade with the doors between front room and dining room, can't you rearrange that corner with the 45degree angle that ends nowhere?
I always like a little storage room for food, hoover, cases of beer and water. Might be able to fit that into the constellation with the toilet.
Agree with the boiler ideas; you want to have an air outlet.
A penny for the hive mind's thoughts...
In the process of buying a 3-bed mid-terrace that looks a bit like this (first time using sketch-up), with possible plans scribbled on as follows (in addition to general renovation/updating):
Any major flaws in those plans? Things you'd do differently, or better ideas?