It would, but it’s designed for Threadripper motherboards that share the same socket as EPYC but are usually oriented at 90deg.
All other correctly-oriented EPYC heatsinks are tiny, made for 1U/2U chassis and are much shitter at cooling a ~200W CPU than the Noctua at a jaunty angle.
+rep
These will sit quite close to humans, hence the 4U chassis and big, slow-spinning hearing-aid-beige cum dysentery-brown Noctuas.
Nothing else comes close for static pressure per rpm /sfss