Should you grease dropouts/hubs/axle?

I’ve never personally done so and I’m pretty on it with greasing everything else. Never had an issue myself from not having this area greased but maybe I’m just lucky!

Hi Leslie.
There is no thread that doesn’t need some. Steel meets steel threads are worse when small, like bottle bosses and rack mounts, but no reason why threaded axles / wheel-nuts shouldn’t have a dab. I would avoid using lots as the nut and dropout may want to be grippy (fixed wheel on track ends or horizontal dropouts) , so only a tiny bit inside the nut threading not on the faces where they grip.

The interfaces to really be careful of are where alloy and steel meet and might stay there for a while, with no threading, such as seat posts /seattubes and quills / threaded steerers.

There is some debate about whether cranks and BB spindles should have grease. Otherwise, always grease.