If the thread corresponds to the needle hole (ie thick thread = big needle), it should be possible when the foot is up.
The foot up/down mechanism also compresses the thread tension dial; When the foot is down, it compresses a spring in the dial, giving the true rate of tension for the thread. When the foot is up, it releases the spring/tension, allowing you to pull the work away from the needle after sewing, or thread the machine.
If the thread corresponds to the needle hole (ie thick thread = big needle), it should be possible when the foot is up.
The foot up/down mechanism also compresses the thread tension dial; When the foot is down, it compresses a spring in the dial, giving the true rate of tension for the thread. When the foot is up, it releases the spring/tension, allowing you to pull the work away from the needle after sewing, or thread the machine.