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I don't think so. I mean, if you specifically want LS50s, get 'em.
One thing I will say is if you have CA floorstanders and move to LS50s you're losing a lot of lower frequencies. So I'd be cautious of that. The lack of low end is one of the main reasons I returned my Meta's.
Not sure what CA you have but the SX-80 freq response is: 40Hz – 20kHz
And the Meta's: 79 Hz - 28 kHz
Those are very different sets of speakers...
Is this the old Sonos Amp or new one? I mean, the new one has enough watts to push 'em, so if you can get them somewhere that accepts returns then you have nothing to lose by trying. Or even just demo them somewhere.