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See an amateur like me or you would spec 650 48 + guards but that would just encourage greedy piggies to fit 27.5 X 2.1 without guards, ride around in some godforsaken bog path in November and say things like "full send"
650 X 42 means you're forced to use overpriced, fragile and imported tyres like Rene herse or gran Bois which you can nurse around lanes, as God intended.
Only adjustment I'd make is clearance for 650x48 and guards, other than that you've got it pretty much spot on.
Maybe you should design bikes for a job, you seem to have a knack for it.