You have a 46 up front, not a 50.
What I mean is if you need a 34 x 42 (silly distance or elevation, loaded bike, combination of both, do you really need a 50 x 11?
EDIT: and a 46-30 with an 11-36 would have the same lower gear, with a less gappy cassette.
I'm struggling to find a scenario where such a pairing makes sense.