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I was joking but the thought did cross my mind when wondering how much my missus could ride on 25mm road tyres. She just walks bits and I thought "Hey I walked stuff in Badlands, I could just walk a bit more stuff" but yeah, I also rode way more so it's definitely a false economy. Maybe for longer rides/races I'd think about going a bit skinnier, simply because the 50mm I have up front is pushing the clearance limits.
Assuming that'd be an endurance race, your body would take the biggest toll probably