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yeah I shuck external hard drives all the time - often it's a cheap way to get large HDs to upgrade my NAS storage. Amazon and other large retailers often do 25%+ discounts on WD elements drives for short runs, which contain WD white drives, almost identical to WD reds. Last one I picked up was a 14tb WD white for under £150, when the equivalent WD red costs around £360. In some cases you'll need to insulate one of the 3.3v terminals to get a drive to work but with SATA drives the jumpers really don't do much anymore.
Has anyone tried taking 3.5"HDDs out of USB enclosures to use in a machine? Online it seems to vary from just take it straight out through to having to change jumpers and whatnot