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As @giofox said, I run a R7000 4iiii with a GRX600 chain set. I started off with a pedal spacer on the NDS to even out the q factor, but I think I forgot to put it on when I last changed the pedals.
Not sure if GRX stages etc are available yet, but the GRX600 crank isn't flat at the back so I think they were only making a 800 series one.
Thanks! Thought as much, hollowtech 2 all seems pretty mix and match-able. Just wondered if they'd messed with the spline and/or axle length as they've moved the chainline out a bit.