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This guy has 46T with Wolftooth, so depending on your bike I'd guess 40T would work. I've run 42T on 8050 with no Wolftooth and it's the same RD shape so you should get most of the way there.
https://www.ridinggravel.com/forum/?p=%2Fpost%2F4634-1140t-di2-custom-drivetrain-10419457
No... as I said, it's like I've got an 8-speed groupset now. Will connect my 8050 mech to the shifters on this bike but given it doesn't shift when connected to the other di2 bike, I doubt it'll make a difference to the mech.
Anyone know if the RX805 mech will fit a 40T cassette like 8050 does?