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Drawback to Nest... it's really "boiler on" and "boiler off"... and that can be crappy if you have a large house and lots of radiators as you're always heating the whole house.
You can do zones though, we have two in our one bed flat, works well but our bedroom radiator is always off so we effectively have three zones but two Nests, if that make sense.
I'd agree Nests don't seem ideal for large houses which is a shame as I really like ours too.
I have Nest, I like it a lot. Excellent at "reach temperature by a point in time" and "learn when I manually change the heating and modify my schedule in future like that". It works when the internet is down (i.e. locally), and has nice thermostat, etc.
Drawback to Nest... it's really "boiler on" and "boiler off"... and that can be crappy if you have a large house and lots of radiators as you're always heating the whole house.
Tado is a radiator TRV that will automatically adjust radiator TRVs and turn the boiler on/off... such that you can control which rooms are heated to what temp and when.
I'd argue Nest is better for US style HVAC systems and smaller UK properties (where you don't care if the whole space is heated so much), and Tado is better for larger UK properties (multi-level 3+ bed homes) where you don't want to heat the whole thing.
But all of these can be changed in future, as they're just a control that adjusts boiler on/off.