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I had blood tests done in early January as the doc thought my calcium levels might be low (they weren't) and was slightly deficient in vitamin D, so have taken a supplement since - I continued taking it all through summer and might up my dose going into winter, sneezing in public is a nerve-wracking thing. I have a really shitty diet though so kind of need supplements.
I'm generally against messing around with the body's natural balance, but after my dad's repeat mentions of it, and cutting down my meat intake, I looked into B12. I couldn't find anything that explicitly warned against taking B12, and it's one of the more common deficiencies (along with vit D).
There are certainly dangers to knocking back any and all supplements you can get your hands on (like vit C as you mention).
I'd be interested to get some blood work done to see if there are any noteworthy deficiencies there, but that will probably have to wait until post-pandemic.