Also, with possible side effects including headaches - I worry that if loads of people get wiped out by headaches for a couple days after dose 1, how keen will they be to get the bigger dose 2 a few weeks later? Like you say, drop out rate could be significantly higher in general population.
Also, with possible side effects including headaches - I worry that if loads of people get wiped out by headaches for a couple days after dose 1, how keen will they be to get the bigger dose 2 a few weeks later? Like you say, drop out rate could be significantly higher in general population.