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yea for sure i use both. 50 x 11 isn't really necessary per say but i like ripping descents. particularly will use it to sprint into them or on flat sections in the middle of one. this is on a bike that does lots of big mixed surface rides, so can have steep unrelenting gravel and also loads of road. 48/31 x 11-34 maybe would be slightly more optimal but that'd mean grx fd, crank (not available in my preferred length), new pm, etc.
zmjones_
But why do you need that much range? If I'm on a ride where I might need a 34-40, there's no way I'm going to need 50-11.
Di2 is good, but you still can't brake at the same time as shifting without some crazy finger contortions.