-
Yes indeed. The new GRX cranks have 110 BCD for the outer ring and 80 BCD for the inner ring.
My advice if you want ultra-low gearing on 2x is to buy a GRX crankset and a GRX front derailleur. You need to get the derailleur too because the chain-line for GRX is 2.5mm outboard.
mind_maze-
In case it helps anyone: my Specialized Sequoia came with an FSA chainset that's 48/32T and works with a standard 105 front derailleur. The cassette is an 11–36T Sunrace and also works with a 105 derailleur (GS cage but no extender as far as I am aware). So it's possible to make a non-GRX Shimano road setup work. Though I don't know if I would have necessarily gone for this exact setup had it not come with the bike.
Pictured with 1.9" 650B Gravel Kings (probably the largest tyre that the chainstays will clear).
-
I’m using di2 so its sounding like grx cranks are an expensive upgrade despite the cranks being pretty cheap
AntSel
atz
Stronglight have 44, 46, 48 and 49T outer rings to fit 4-bolt Ultegra/105.
Their smallest inner ring is 34T though, which I think is a limitation of (non-oval) chainrings with 110 BCD. So if you want 32T or smaller you need either an oval chainring or a different crankset (e.g. FSA, GRX).