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Yes; all else being equal, for a given size a cup and cone bearing can be larger and thus stronger, and can in most bicycle applications have the preload adjusted more accurately. Sealing against water and grit will depend on the quality of the seals in each application, rather than being a matter of cartridge vs cup and cone. Which is better for a given application is going to depend on the relative quality of sealing and ease of adjustment/ease of bearing replacement, but in general I would expect decent quality cup and cone pedals (e.g. MKS/Shimano) to last for decades with an annual strip and service.
Thrustvector
oatmeal
Interesting view - so you think unsealed will outlast sealed as long as you keep them correctly adjusted and greased?