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When you're on the bike, your weight should cause the suspension fork to move into its travel slightly. This allows the fork to extend into small holes in the road/trail and better maintain grip
For a 100mm travel fork, your 'sag' should be around 20-25% of that travel. This will steepen your seat & head angle and lower your BB to what the geometry was intended to be
Another way to look at it is your sus fork is about 500mm in length, but if you wanted a rigid fork on there, you'd be looking for one with an a-c of 480mm
Lockouts can be useful for a sprint to the finish line, but for the rest of the time they're a bit meh
The real question is why you would buy an expensive race fork and then lock it out
Set it up properly so that it rides at its' proper sagged height and doesn't mess up the bike's geometry