Modern road bike with disc brakes... what can I get these days?

Hello there lovely people,

Due to prolapsed disc in my back, I have sold my road bike (a lovely Serotta that was listed here a while ago). I’m only riding my gravel bike now. I’ve transformed that into a more road friendly and I sort of feel comfortable on that.
Now, when my back finally fixes itself (hopefully not long now) I’ll be looking to get a new (but probably 2nd hand) road bike with disc brakes. I’m nowhere near a lightweight cyclist, so I’ll be looking at some nice steel or titanium frame (although will listen to carbon ideas too). I used to work in the cycling industry but that was over 5 years ago and it seems like I’m no longer “up to date” with all the gear.
So, with a budget of £2k ish, what could I be looking at? Ideally, I’d like a full package rather than basic wheels that will need upgrading. I don’t need any top tier group sets - Shimano 105 works perfect for me. Would it be better to buy all the bits separate and build the bike myself (as I’ve done with the Serotta)?
Thanks

If you want “up to date” and need a more relaxed road bike for the back, I'd give a Canyon Endurace a look.

The Carbon 7.0 disc and Al 7.0 disc are in budget. By the time you source a half decent frame, r7020 groupset & parts, the saving might not be that big.

https://www.canyon.com/en-gb/road-bikes/endurance-bikes/endurace/

Thanks. Well, I’m just poking around at the moment. And with discs, that means an thru axle, and that means modern, doesn’t it?
I’d love a nice titanium or stainless steel frame, I see a nice one on eBay but they don’t come up very often. Or I don’t look hard enough.

Freeborn sale going on for genesis bikes.

Thanks. Well, I’m just poking around at the moment. And with discs, that means an thru axle, and that means modern, doesn’t it?

Modern right now is 12x100 / 12x142 thru axles, flat mount disc brakes and clearance for 28-32mm tyres.