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Cheers @gbj_tester and @Thrustvector.
50g is about a large mouthful of water or the reduction in weight from an Dura-Ace component to a 105. I was curious to work out the actual impact in energy expenditure of a reduction in the mass moved by the rider. More complex a question than I reckoned.
Adhiero
For that case, the mass is all but irrelevant, but the thinner walled tubes will have smaller hysteresis loss if made from the same material. That effect will massively overdominate any effect from the difference in mass.