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Yes - have bought and sold independently, and no.
You have to do all the negotiating yourself, obv and if you're in a chain you'll have to deal with EAs at the other end. But solicitors do the detail stuff as per usual so it's really just a bit more keeping up with communication once you've agreed prices etc. Having no EA fees gives you an extra bit of virtual cash to share to sweeten the deal.
Has anyone sold a property without using an estate agent? Any particular complications that this adds to be aware of?