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What type of leather, shiny or suede? Clothing or furniture? Get warm water and a little Fairy washing up liquid or similar and use a cotton wool bud and dab a little at a time. Keep the bud clean and change frequently. Don't get it too wet as it may leave tide marks. I've just done the arm of a suede chair - bike grease. It worked but you can't rush it.
What can I try to use to remove biro ink from leather?