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The sensitivity and specificity aren't changing. The derived accuracy of a result changes depending on how prevalent the condition is amongst the tested population as the relative
The less prevalent the condition is in the population the more false positives you'll get.
The more prevalent the condition is in the population the more false negatives you'll get.
Both of these factors affect the eventual accuracy. See: https://www.lfgss.com/comments/15296147/
What are you doing to get a shift in sensitivity/specificity based on an outside factor?