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So I had the originals and have run in the infinitys.
I wouldn't recommend the epic reacts but would recommend the infinity's.
They're both super comfy, the flyknit is really comfy (much prefer to the plastic Zoom material), the tongue being part of the shoe means the lace really well (Something I can't say about the Peg turbos!).
The Epic reacts I felt just didn't have enough lateral support and were slippy. This seems to have been addressed with the infinity's. I saw that Jack Rayner has been running in the Infinitys on some of his longer training runs which probably bodes well for their suitability over those distances.
I do.