Just started running in zero drop shoes and can report my calves are sooo sore! Switched due to knee pain and can also report I have no knee pain! And I was running in very cushioned Hokas - heel strike just fucks me up.
Certainly something you want to ease into. I’ve used a pair of Newbalance Minimus shoes on and off for a few years and they can be a hard surprise on the body at first. They’re great for lifting in though.
https://theconversation.com/running-shoes-may-cause-injuries-going-barefoot-could-be-the-surprising-fix-135264