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I do.
Usually you've clicked on the cells already, or use F5 to enter them.
Although my colleague alternates his mousehand half way through the day, so presumably all ambimousetrous use their left hand when numberpading.
I go back and forth on getting a nice small mechanical keyboard, but honestly I like having the numberpad. The laptop I'm using WFH has one, and I notice the lack of one on my personal one.
Not hugely exciting, but I haven't found any other left handed mechanical keyboards. I would hate to go back to using a righty now for workflow reasons, this makes so much more sense when you're using the mouse and numpad a lot, and besides it's fun watching the confusion on peoples faces when they use my computer.