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I used to lug my laptop back and forth (2 days WFH, 2 days in the office) but then I got a desktop in the office and leave my laptop at home.
Luckily any meetings I have to host are all through Webex so I can do them from either (I don't need my laptop to go to a meeting room in the office). For meetings hosted in the office by others it's fun turning up with a pen and paper whilst everyone else is sat there tapping away on their laptop (drives me nuts).
I've been cycling my laptop to and from work for three years now (i work from home twice a week). In a carradice but without the laptop I would probably only need a small handlebar bag. So glad it's not my own laptop. Would be lovely to be able to leave it at work but working from home is a bliss.