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I'm using fatter tyres than I used to - 28s rather than 25s - and running them at more like 70psi than 100psi so it is probably less of an issue than when I had nightmares in TCR 2016. But it's mostly luck if you get tyre problems. I'd probably not bother with them at 120psi for skinny tyres.
My winter / commuting bike also has 28s (I need to use an extra cable tie to keep the mudguard from rubbing) but I don't bother pumping the tyres up until they are really soft, and it's fine. As long as I don't bump up kerbs!
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I've always run 28mm w/ tubes except maybe one Trans Am I ran a 25mm up front and regretted it. I normally start around 90psi and let them go down from there.
People seem to be running TL for TTs though. Maybe it's fine because the short distances means far less risk of a tyre failure and if you do have a failure your race is pretty much over anyway and a sealant fix might even get you around to the HQ. I'll stick with tubes for TTs though.
My winter/commuter has a 35mm front and 42mm rear. I got my gravel tyres inflated on the weekend with the sealant in 'em so it might soon have 47mm f/r :)
Go big or go home, they said...I'm the same. I used to put air in my old 23s and 25s on the Ribble and they'd be down to like 2-3 bar and I'd notice because I'd have to be real careful hopping the curb at home.
According to TyreWiz I should only be running 46/36psi in my tyres now but I'm not sure about that. I'd don't trust myself with the state of the roads not to run into a random pothole.
Yeah, I'm still not convinced about TL for road tyres. The high pressure seems to render a lot of fixes problematic and the crazy tight tyre beads mean roadside tube insertion or patching are jokes. For low pressure MTB and gravel use then I get it but I'm leaving tubes in the road bike for a while yet.