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always remove core to add, sealant clogs up the presta mechanism.
This.
Also remove core when you blast the tyres to get it to seat, not always necessary (especially if you can just pump up the tyres) but make a big difference if you struggle.
If you're fitting a new tyres on, it's sometime just easier to pour in the sealant from a unseated part of the tyres.
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always remove core to add, sealant clogs up the presta mechanism otherwise and always at 7 o clock position