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It's definitely worth it if you can get some extended time off - it was our honeymoon so employers couldn't say no to a month really :)
We were hiking from the 6th to the 21st with one zero day on the 11th. Our permit started in Tuolumne Meadows in Yosemite and headed out over Kearsarge Pass, which was about 3 days before the official end of the trail. Walking from about 8am to 4pm each day with about a 30 minute lunch break. The most I had in my pack was about 16kg including two litres of water - definitely too heavy but that also included 7 days of food from a resupply (although we ran out early...).
Weather-wise it was mainly hot and sunny, dropping to freezing overnight. Had a couple of minor snow / hail storms that were actually quite fun, although did cause some worry about ice over the higher passes (we crossed five that are above 11,000ft).
Some unsolicited pics attached as this gave me an excuse to look at them again...!
For anyone interested I'm just back from the John Muir Trail in California. It was absolutely brilliant. Physically very demanding, but so beautiful. My wife and I haven't been thru-hiking before, so this was a bit of a challenge but we loved it. Planning our next adventure already (suggestions welcome)!
The only thing I'd change was footwear - I used pair of reasonably well worn in gore tex hiking boots, but they gave me blisters about 130 miles into the hike. I ignored backpacking forum advice to wear trail runners that breathe, because who expects rain in CA, and I think the moisture got me. By the end of the day my socks were literally steaming when the boots came off.
If anyone is tempted to do it would be happy to help with itinerary, kit list, suggestions on where to pitch a tent etc etc!