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Like 11-28 vs 12-25 or 11sp vs 8sp?
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Smart turbo? You generally stay in one gear so it likely won't matter. The only thing to be wary of is the extremities - you don't want to move to something where the cassette is bigger and you're stressing the RD trying to fit a too-short chain around some combo.
dbr
hippy
@GoatandTricycle
Anyone run a different size cassette on bike to their direct mount turbo?
Is there a range limit or just a no no