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I'm contemplating this too, though the 700x40 or 42 my bike can fit with decent clearance is great for what I use it usually but 2" or 2,1" would be better for some adventurous races.
Wtbs seem to be good and cheap, stans crest is really light and said to prevent pinch flats on tire wall. Hunts would be the easy option and would have a Son hub.
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Inner tubes or other stuff for 650b will be almost impossible to find in Morocco. But since 700c is not an option for me, I am planning on riding Morocco Bike Adventure on DT swiss XR 391 rims (32 holes), WTB Byway.
If someone was to say ride something like https://www.transiberica.cc/badlands/ or https://atlasmountainrace.cc/ and had a bike that could use 700C wheels or 650B wheels with fatter rubber fitted and felt a desire to use said fatter rubber of the 650B option, what wheels would they look at and what tyres?