700c? No. Not 1-cross. The Alfine / Nexus has a large flange but still. I would have built it 3-cross. Perhaps 2-cross if I was using an eyeletted rim where the nipple angle wasn't quite right. Even the hub manufacturers such as Rohlhoff or Powertap recommend 2-cross.
700, DT R460DB
No reason to lace an Alfine / Nexus on a 700 rim in such an esoteric way I’d have thought.