700c? No. Not 1-cross. The Alfine / Nexus has a large flange but still. I would have built it 3-cross. Perhaps 2-cross if I was using an eyeletted rim where the nipple angle wasn't quite right. Even the hub manufacturers such as Rohlhoff or Powertap recommend 2-cross.
I've built up 1-cross but only with large flange hubs laced to small rims, such as a Rohlhoff on a Moulton rim. How big is the rim?