• 1950:

    https://en.wikipedia.org/wiki/Motor_Mania

    The cartoon shows how the character, as the pleasant, friendly, and
    good-natured "Mr. Walker" who "wouldn't hurt a fly nor step on an
    ant", undergoes a change in personality to the violent "Mr. Wheeler"
    when he gets behind the wheel of his yellow car. As Mr. Walker he's
    polite, safe, and good-natured while as Mr. Wheeler; he is very mean,
    reckless, and predatory.

    Mr Walker/Wheeler- Goofy.

    (Mr. Walker makes a cameo reading a newspaper in Toontown in Who Framed Roger Rabbit.)

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