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Both would require you to adjust the non actuated side, I.E. The brakes above and BB5 AND 7 AND the actuated side, 5 by pulling the cable, 7 via the red outer knob.
Which means that even though Sypres are dual actuated and even IF you set it dead center you would then adjust both sides the same to get the same dead center bite.
You always have to adjust for pad wear with a mechanical brake regardless of whether the second side moves or not. If you only use the cable adjuster, you end up with a really dead-feeling brake.