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faster
Theoretically, following the canal is 1 mile longer but takes about 5 minutes less. It has the advantage of being dead flat and avoids the absolute shit show of traffic jams involved in going up every west London high street which is what the Uxbridge Road involves. Even if it took slightly longer, it's still the way I'd go just for the reduction in NOx & PM2.5 inhalation.
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@NorthLondonLight knows that route in detail I think
Is there a faster way to ride from Lisson Grove to Hillingdon Cycle Circuit than going down Sussex Gardens, and all the way along the Uxbridge Road?