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it's great, I'm almost never at home in London these days so never get to play but it's still one of my faves.
my one non-spoiler'y tip for starting out is pay attention to donating to receive blessings when in town, I recommend doing so whenever you have the gold early on as the blessing cards will help a bunch.
I don't use it myself but apparently the gloomhaven helper app/website is very good for reducing the mess on the table as it handles all the monster cards/hit points for you.
and finally a storage organiser will improve your enjoyment of the game a hundredfold as the setup and teardown times can be brutal without it.
After a lot of dithering I finally pulled the trigger and bought Gloomhaven. What a monster; you do not want to drop the box on your foot. Still working my way through the manual but very exited about this purchase!