No reason why not, the climb out of Nice will be tough but not as tough as the first climb going south. The Finestre descent would be a highlight. I wouldn't advise climbing the Strada Cannoni section but alternative section there, the death road up to Elva, is a nice road climb.
Agnel/Agnello south side ... of all the roads I've ridden down that have given me the fear of ever climbing back up that way, that's probably top of the list.
No reason why not, the climb out of Nice will be tough but not as tough as the first climb going south. The Finestre descent would be a highlight. I wouldn't advise climbing the Strada Cannoni section but alternative section there, the death road up to Elva, is a nice road climb.