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I'm not particularly fussed about Samsonite or not. I've got a few criteria that very few bags seem to meet.
Backpack (one with decent straps and a padded back so you can carry it for a while if needs be).
Clamshell for easy packing/access.
Upper end of hand luggage size (40-50 litres).
Decent number of usable pockets for laptop, kindle, toiletries, etc.I'm not that fussed by looks (the Samsonite one looks ok in real life but not great).
Not much matches those requirements, looking at the Tom Bihn one for instance the ones in that style are a bit small (although I may look into them as a weekend bag).
I thought he was more of a briefcase guy