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Well, I asked that question myself a while ago, and all in all, this is what people said: technically, a slight (very slight) amount of power savings due to the chain turning radius being larger, a slight decrease in wear for the same reason, and... better looks. That's pretty much it. Oh, but a slightly higher weight though. None of this is super important for someone who isn't racing at a relatively decent level, I don't think.
The thing about gearing though is that 59/21 (2.81) or 60/21 (2.86) is almost the same ratio as 48/17 (2.82), but it LOOKS more extreme. ;)
Yeah did see that, still looks mad overall. Any benefits fitting big sizes either end?? Yeah, looks wise got to have that high to low ratio, legs don't always agree though.