Would rim brakes acting on the rim, and so both sides of the wheel relatively evenly and disk brakes acting on one side of the hub, so acting slightly differently on each side of the wheel change the forces involved to affect the spokes differently?
Yes, because the hub shell does not have infinite torsional stiffness, the rotor side spokes do the heavy lifting. This is exactly the same as the situation with the drive side of the rear hub.
Would rim brakes acting on the rim, and so both sides of the wheel relatively evenly and disk brakes acting on one side of the hub, so acting slightly differently on each side of the wheel change the forces involved to affect the spokes differently?