yes, I use it on all my bikes that cant / dont have a tubless set up. Just remove the valve core, squirt in some tubeless sealant, recore and inflate. I have only have positive results on many bikes of my families, customers and buggy wheels with impossible to remove systems!
Does sealant in 700c inner tubes work well? I'm reading conflicting things on other sites, so it's hard to get any information on it.