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Tychom
No it's a non issue (unless baths and electric current are involved) as far as bikes are concerned. SO long as appropriate welding/brazing rods are used there's no issues with mixing stainless and non-stainless.
Cool what's the build? Far and away the biggest component in determining the stiffness of a tube is the size and shape, I'd be very surprised if you could tell the difference between any OS tube sets of equal diameter. It's a while since I've looked through the Reynolds catalogue but if I remember correctly 853 only goes up to a 35mm DT so you may want to look at Columbus offerings. There's other reasons to choose a tube though and 853 is an absolute world away from anything Columbus make in terms of toughness. It may or may not make a difference on the bike but it's a lot more robust.