Doping

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deleted

some interesting nuggets of infor in the Guardian q+A:

There is no evidence that this substance has any beneficial effect on performance, lets try to keep a sense of perspective.

Sean replies:

User avatar for seani Guardian staff seani 14 December 2017 1:38pm
There are two points worth making in response here:

1) There is a limit set by the World Anti-Doping Agency and Chris
Froome has exceeded it by twice the permitted out.

2) There is some evidence that Beta 2 Agonists can improve performance
(See here: Inhaled Beta2-Agonist Increases Power Output and Glycolysis
during Sprinting in Men.) I was also speaking to a sports scientist
yesterday who made the point that a lot of those studies claiming no
benefit to Beta 2 Agonists do not use particularly relevant (to elite
sport) dosages of the drug under investigation and most importantly
use a performance measure (like VO2max) that is irrelevant to an
athlete like Froome.

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gbj_tester in reply to @deleted

a lot of those studies claiming no
benefit to Beta 2 Agonists do not use particularly relevant (to elite
sport) dosages of the drug under investigation

Depends what you're trying to prove. Most of the studies I've seen are testing the performance enhancing effect of therapeutic doses of inhaled drugs, to determine whether giving TUEs to asthmatics has unintended consequences. Testing large systemic doses (e.g. 4-8mg orally) is a different matter, but that kind of regime would be an out of competition thing, you'd have to be unbelievably stupid to keep it up in the racing season.

use a performance measure (like VO2max) that is irrelevant to an
athlete like Froome.

Did I miss a meeting? Surely VO₂max is pretty relevant to a GC contender.

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