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Ummm I know allergies I had terrible ones as a kid to dust mites and cats, my nose would just piss away, eyes swell, asthma, headaches it was horrible.
These days nothing. Even cats. No treatment worked when I was younger, parents tried everything under the sun, pills, nasal sprays, inhalers, homeopathy, literally everything. But it just stopped but I remember what it was like.
Are you suggesting allergies can't develop later in life or change based on location? Or that the best treatment for an existing ailment not change over time?