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@Heldring @frankenbike thank you for the feedback. I'm learning here.
@mdcc_tester
The slight inconvenience, I take, is a different spoke length, for an otherwise nice smooth build with same spoke length on a symmetrical rim?
sykodrama-
The slight inconvenience, I take, is a different spoke length
For symmetrical hubs laced to asymmetrical rims, yes.
For asymmetric hubs laced to symmetrical rims, it might not even amount to that because although that can lead to a difference in spoke length from side to side, it might not if the hub designer has made the flange diameters different, and using an asymmetric rim will only yield equal length spokes if it's just the right offset and the hub wasn't already designed to use equal length spokes in a symmetrical rim.
gbj_tester
Yes, but the problem is less dramatic due to the smaller difference between left and right flange offsets. Apart from the slight inconvenience while building, disc fronts with non-offset rims and non-disc fronts with offset rims will both be fine, in the sense that if you're really running that close to design optimisation on a front wheel that it will make a material difference, you should probably consider adding a bit more safety margin.
In a rare example of something new actually being an improvement, Boost™ can actually solve the problem for front disc hubs.